A/Prof Cameron Holloway

bio-cameron_holloway

Associate Professor Cameron Holloway was appointed to St Vincent’s Hospital in 2012 after returning from Oxford, UK, where he has worked for 6 years as a Consultant Cardiologist and as an academic with the University of Oxford.

Cameron graduated from Monash University in Melbourne. He completed his physician training in both the UK and Australia and his cardiology training at St.Vincent’s Hospital in Sydney, prior to moving to the University of Oxford where he trained in advanced cardiac imaging. His PhD and post-doctoral research focused on assessing mechanisms of heart disease using cardiac MRI. He has a particular interest in metabolic heart diseases, including complications of diabetes and HIV.

He has an interest in education and has published widely, whilst supervising over 12 honours, masters and PhD students. He was recently awarded a 5 year Australian Heart Foundation Life Science Research Fellowship, which will help develop advanced imaging techniques in Australia.

As a general cardiologist, Cameron sees patients with a wide range of cardiac diseases and uses advanced cardiac imaging techniques, including cardiac MRI for the assessment of cardiovascular disease.

 

  • MBBS(Hons1), MRCP (Lon), FRACP, CSANZ, D.Phil (PhD, Oxon)
  • Cardiologist & Cardiovascular Imaging Specialist, St Vincent’s Hospital, Sydney
  • Conjoint Associate Professor of Medicine
  • University of New South Wales
  • Australian Heart Foundation Life Sciences Research Fellow
  • Clinical Faculty, Victor Chang Cardiac Research Institute
  • Australian Heart Foundation Clinical Life Sciences Fellowship (2012-2017)
  • Level 3 Cardiac MR- Society of Cardiovascular Magnetic Resonance (2012)
  • Young investigator Award, Society for Cardiovascular MR (SCMR), Phoenix, USA (2012)
  • Young investigator Award, British Society for Cardiovascular Research (BCMR), UK (2009)
  • First Prize Birmingham Altitude Research Conference for oral Presentation, UK (2009)
  • European Scholarship holder for SCMR 2009, Orlando, USA (2009)
  • Finalist in Clinical Young investigator award, Clinical, SCMR, Orlando (2009)
  • University of Oxford Academic Merit Award- Awarded by Professor Sir George Radda (2008)
  • University Registrar Tutor of the Year, University of New South Wales, Australia (2004)
  • St Vincent’s Hospital Registrar award of the Year, Sydney, Australia (2004)
  • Arthur Clarke Award in Paediatrics- top medical student in Paediatrics, Monash University (200)
  • Finalist Harriet and Robert Power Scholarship in Medicine (top 3)
  • Finalist Harriet and Robert Power Scholarship in Surgery (top 3)
  • Royal Australian Medical Undergraduate Society Scholarship
  • Australian Health Award- Outstanding Achievement in Health Promotion (1997)
  • Cardinal Knox Academic Scholarship, Mannix College, Monash University (1996)
  • Cardinal Knox Academic Scholarship, Mannix College, Monash University (1995)
  • Ridley College, Academic Scholarship, The University of Melbourne (1994)
  • Perram J, Joseph J, Holloway C. Novel oral anticoagulants and HIV: dabigatran use with antiretrovirals.BMJ Case Rep. 2015 Nov 20;
  •  Levelt E, Rodgers CT, Clarke WT, Mahmod M, Ariga R, Francis JM, Liu A, Wijesurendra RS, Dass S, Sabharwal N, Robson MD, Holloway CJ, Rider OJ, Clarke K, Karamitsos TD, Neubauer S. Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus. Eur Heart J. 2015 Sep 20.
  • Dass S, Holloway CJ, Cochlin LE, Rider OJ, Mahmod M, Robson M, Sever E, Clarke K, Watkins H, Ashrafian H, Karamitsos TD, Neubauer S. No Evidence of Myocardial Oxygen Deprivation in Nonischemic Heart Failure. Circ Heart Fail. 2015 Nov;8(6):1088-93
  • Dass S, Cochlin LE, Suttie JJ, Holloway CJ, Rider OJ, Carden L, Tyler DJ, Karamitsos TD, Clarke K, Neubauer S, Watkins H. Exacerbation of cardiac energetic impairment during exercise in hypertrophic cardiomyopathy: a potential mechanism for diastolic dysfunction. Eur Heart J. 2015 Jun 21;36(24):1547-54
  • Wang LW, He EY, Ghosh D, Day RO, Jones GR, Subbiah RN, Holloway CJ. Severe carbon monoxide poisoning from waterpipe smoking: a public health concern. Med J Aust. 2015 May 4;202(8):446-7
  • Banerjee R, Rial B, Holloway CJ, Lewandowski AJ, Robson MD, Osuchukwu C, Schneider JE, Leeson P, Rider OJ, Neubauer S. Evidence of a Direct Effect of Myocardial Steatosis on LV Hypertrophy and Diastolic Dysfunction in Adult and Adolescent Obesity. JACC Cardiovasc Imaging. 2015 Dec;8(12):1468-70
  • Davis AE, Lewandowski AJ, Holloway CJ, Ntusi NA, Banerjee R, Nethononda R, Pitcher A, Francis JM, Myerson SG, Leeson P, Donovan T, Neubauer S, Rider OJ. Observational study regional aortic size referenced to body size: production of a cardiovascular magnetic resonance nomogram. J Cardiovasc Magn Reson. 2014 Jan 21;16(1):9.
  • Holloway CJ, Murray AJ, Mitchell K, Martin DS, Johnson AW, Cochlin LE, Codreanu I, Dhillon S, Rodway GW, Ashmore T, Levett DZ, Neubauer S, Montgomery HE, Grocott MP, Clarke K. Oral Coenzyme Q10 Supplementation Does Not Prevent Cardiac Alterations During a High Altitude Trek to Everest Base Camp. High Alt Med Biol. 2014 Mar 24.
  • Cheruvu S, Holloway CJ Cardiovascular disease in HIV. Intern Med J. 2014 Apr;44(4):315-24.
  • Codreanu I, Pegg TJ, Selvanayagam JB, Robson MD, Rider OJ, Dasanu CA, Jung BA, Taggart DP, Golding SJ, Clarke K, Holloway CJ. Normal values of regional and global myocardial wall motion in young and elderly individuals using navigator gated tissue phase mapping. Age (Dordr). 2014 Feb;36(1):231-41. doi: 10.1007/s11357-013-9535-x. Epub 2013 Apr 21.
  • Rider OJ, Asaad M, Ntusi N, Wainwright E, Clutton G, Hancock G, Banerjee R, Pitcher A, Samaras K, Clarke K, Neubauer S, Dorrell L, Holloway CJ. HIV is an independent predictor of aortic stiffness. J Cardiovasc Magn Reson. 2014 Aug 16;16(1):57.
  • Walton S, Berger K, Thiyagalingam J, Duffy B, Fang H, Holloway C, Trefethen AE, Chen M. Visualizing Cardiovascular Magnetic Resonance (CMR) imagery: Challenges and opportunities. Prog Biophys Mol Biol. 2014 Aug 2.
  • Ferreira VM, Piechnik SK, Dall’Armellina E, Karamitsos TD, Francis JM, Ntusi N, Holloway C, Choudhury RP, Kardos A, Robson MD, Friedrich MG, Neubauer S. Native T1-mapping detects the location, extent and patterns of acute myocarditis without the need for gadolinium contrast agents. J Cardiovasc Magn Reson. 2014 May 23;16:36.
  • O’Rourke M, Holloway CJ, O’Rourke J. The proximal thoracic aorta- Keystone or Achilles heel? JACC J Am Coll Cardiol. 2014 Dec 23;64(24):2630-2. doi: 10.1016/j.jacc.2014.10.010.
  • Ferreira VM, Piechnik SK, Dall’Armellina E, Karamitsos TD, Francis JM, Ntusi N, Holloway C, Choudhury RP, Kardos A, Robson MD, Friedrich MG, Neubauer S. T(1) mapping for the diagnosis of acute myocarditis using CMR: comparison to T2-weighted and late gadolinium enhanced imaging. JACC Cardiovasc Imaging. 2013 Oct;6(10):1048-58.
  • Holloway CJ, Ntusi N, Suttie J, Mahmod M, Wainwright E, Clutton G, Hancock G, Beak P, Tajar A, Piechnik SK, Schneider JE, Angus B, Clarke K, Dorrell L, Neubauer S. Comprehensive cardiac magnetic resonance imaging and spectroscopy reveal a high burden of myocardial disease in HIV patients. Circulation. 2013 Aug 20;128(8):814-22. doi: 10.1161/CIRCULATIONAHA.113.001719. Epub 2013 Jul 1.
  • P Bhamra-Ariza, CJ Holloway The Assessment and Management of Coronary Artery Disease in Patients with HIV Journal of AIDS & Clinical Research. In Press 2014
  • S Cheruvu, CJ Holloway. Cardiovascular disease in HIV Internal Medicine Journal. In Press 2014
  • CJ. Holloway,AJ. Murray,K Mitchell, A Johnson, LE. Cochlin, D Z.H. Levett, I Codreanu, S Dhillon, S Neubauer, H E. Montgomery, M P.W. Grocott, K Clarke High Altitude Medicine and Biology In Press 2014
  • Ferreira VM, Holloway CJ, Piechnik SK, Karamitsos TD, Neubauer S.Is is really fat? Ask a T1 map. Eur Heart J Cardiovasc Imaging. 2013 Nov;14(11):1060.
  • Mahmod M, Bull S, Suttie JJ, Pal N, Holloway C, Dass S, Myerson SG, Schneider JE, De Silva R, Petrou M, Sayeed R, Westaby S, Clelland C, Francis JM, Ashrafian H, Karamitsos TD, Neubauer S. Myocardial steatosis and left ventricular contracile dysfunction in patients with severe aortic stenosis. Circ Cardiovasc Imaging. 2013 Sep;6(5):
  • Codreanu I, Pegg TJ, Selvanayagam JB, Robson MD, Rider OJ, Dasanu CA, Jung BA, Taggart DP, Golding SJ, Clarke K, Holloway CJ. Normal values of reginoal and global myocardial wall motion in young and elderly individuals using navigator gated tissue phase mapping. Age (Dordr). 2014 Feb;36(1):231-41
  • Clutton G, Yang H, Hancock G, Sande N, Holloway C, Angus B, von Delft A, Barnes E, Borrow P,     Pellegrino P, Williams I, McMichael A, Dorrell L. Emergence of distinct HIV-specific IL-10 producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection Eur J Immunol. 2013 Nov;43(11):2875-85. doi: 10.1002/eji.201343646. Epub 2013 Aug 29.
  • Davis AE, Lewandowski AJ, Holloway CJ, Ntusi NA, Banerjee R, Nethononda R, Pitcher A, Francis JM, Myerson SG, Leeson P, Donovan T, Neubauer S, Rider OJ. Observational study regional aortic size referenced to body size; production of a cardiovascular magnetic resonance normogram.  J Cardiovasc Magn Reson. 2014 Jan 21;16(1):9.
  • Holloway CJ, Dass S, Suttie JJ, Rider OJ, Cox P, Cochlin LE, Jackson H, Fast AM, Johnson AW, Karamitsos TD, Neubauer S, Clarke K. Exercise training in dilated cardiomyopathy improves rest and stress cardiac function without changes in cardiac high energy phosphate metabolism. Heart. 2012 Jul;98(14):1083-90.
  • Rider OJ, Francis JM, Ali MK, Holloway C, Pegg T, Robson MD, Tyler D, Byrne J, Clarke K, Neubauer S. Effects of Catecholamine Stress on Diastolic Function and Myocardial Energetics in Obesity. Circulation. 2012 Mar 27; 125(12):1511-9.
  • Rider OJ, Holloway C, Clarke K, Neubauer S. Increasing Plasma Free Fatty Acids in Healthy Subjects Induces Aortic Distensibility. Circ Cardiovasc Imaging. 2012 May 1; 5(3):367-75.
  • Edwards LM, Tyler DJ, Kemp GJ, Dwyer RM, Johnson A, Holloway CJ, Nevill AM, Clarke K. The Reproducibility of 31-Phosphorus MRS Measures of Muscle Energetics at 3 Tesla in Trained Men. PLoS One. 2012;7(6):e37237.
  • Clausen H, Francis J, Holloway C A pensioner with dyspnoea: cardiac magnetic resonance reveals pulmonary embolism. BMJ Case Rep. 2012 Aug 18; 2012.
  • Karamitsos T, Dass, S, Suttie J, Holloway CJ Robson M, Jerosch-Herold,M Watkins H Neubauer S Impaired Myocardial Oxygenation Response during Vasodilator Stress in Patients with Hypertrophic Cardiomyopathy. JACC Imaging In Press
  • Dass S, Suttie JJ, Piechnik SK, Ferreira VM, Holloway CJ, Banerjee R, Mahmod M, Cochlin L, Karamitsos TD, Robson MD, Watkins H, Neubauer S. Myocardial Tissue Characterization using Magnetic Resonance Non-Contrast T1 Mapping in Hypertrophic and Dilated Cardiomyopathy. Circ Cardiovasc Imaging. 2012 Oct 15
  • Rider OJ, Lewandowski A, Nethononda R, Petersen SE, Francis JM, Pitcher A, Holloway CJ, Dass S, Banerjee R, Byrne JP, Leeson P, Neubauer S.Gender-specific differences in left ventricular remodelling in obesity: insights from cardiovascular magnetic resonance imaging. Eur Heart J. 2012 Oct 10
  • Holloway CJ, Cochlin L, Codreanu I, Bloch E, Fatemian M, Szmigielski C, Atherton H, Heather L, Francis J, Neubauer S, Robbins P, Montgomery H, Clarke K. Normobaric hypoxia impairs human cardiac energetics. FASEB J. 2011 Sep;25(9):3130-5.
  • Codreanu I, Robson MD, Rider OJ, Pegg TJ, Jung BA, Dasanu CA, Clarke K, Holloway CJ. Chasing the reflected wave back into the heart: a new hypothesis while the jury is still out. Vasc Health Risk Manag. 2011;7:365-73.
  • Codreanu I, Pegg TJ, Selvanayagam JB, Robson MD, Rider OJ, Dasanu CA, Jung BA, Taggart DP, Clarke K, Holloway CJ. Details of left ventricular remodelling and the mechanism of paradoxical ventricular septal motion after coronary artery bypass graft surgery. J Invasive Cardio. 2011 Jul;23(7):276-82.
  • Holloway CJ, Suttie J, Dass S, Neubauer S. Clinical cardiac magnetic resonance spectroscopy. Prog Cardiovasc Dis. 2011 Nov;54(3):320-7. Review.
  • Myerson SG, Holloway CJ, Francis JM, Neubauer S. Cardiovascular magnetic resonance (CMR)–an update and review. Prog Nucl Magn Reson Spectrosc. 2011 Oct;59(3):213-22. Review.
  • Holloway CJ, Cochlin L, Emmanuel, Y, Codreanu, I, Edwards, L, Scheuermann-Freestone, M. Szmigielski, C. Tyler, D, Knight, N, Saxby, B, Lambert, B, Murray, A, Francis, J. Thompson, C. Neubauer, S, Clarke, K. Impaired cardiac high-energy phosphate metabolism and cognition after five days of a high fat diet, American Journal of Clinical Nutrition, January 26, 2011
  • Holloway CJ, TenHove M, Clarke, K. Neubauer, S MR spectroscopy in heart failure. Review. Frontiers of Bioscience. 2011 Jan 1;3:331-40
  • Laverty H, Benson, C, Cartwright E, Hammond T, Holloway CJ, McMahon N, Milligan J, Park K, Pirmohamed M, Pollard C, Radford J, Roome N, Singh S, Suter W, How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?” British Journal of Pharmacology 2011 Feb 10.
  • Holloway CJ, Montgomery HE, Murray AJ, Cochlin LE, Codreanu I, Hopwood N, Johnson AW, Rider OJ, Levett DZ, Tyler DJ, Francis JM, Neubauer S, Grocott MP, Clarke K; Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp. Caudwell Xtreme Everest Research Group. The FASEB Journal 2011 Feb;25(2):792-6.
  • Holloway C, Clarke K. Is MR spectroscopy of the heart ready for humans? Heart Lung and Circulation. Review. 2010 Mar;19(3):154-60. Epub 2010 Feb 24.
  • Holloway CJ. Edwards, L. Rider, L, Fast, A. Clarke, K. Francis, J. Myerson, S. Neubauer, S. Eyeball assessment of left ventricular function, compared to quantitative assessment by cardiac magnetic resonance. International Journal Cardiac Imaging Oct.2010 Volume 27, Issue 4 (2011), Page 563-569.
  • Edwards LM, Murray AJ, Tyler DJ, Kemp GJ, Holloway CJ, Robbins PA, Neubauer S, Levett D, Montgomery HE, Grocott MP, Clarke K; Caudwell Xtreme Everest Research Group. The effect of high-altitude on human skeletal muscle energetics: P-MRS results from the Caudwell Xtreme Everest expedition. PLoS One. 2010 May 19;5(5):e10681.
  • Edwards LM, Murray AJ, Holloway CJ, Carter EE, Kemp GJ, Codreanu I, Brooker H, Tyler DJ, Robbins PA, Clarke K. Short-term consumption of a high-fat diet impairs whole-body efficiency and cognitive function in sedentary men. The FASEB Journal. 2010 November 24, 2010
  • Karamitsos TD, Ntusi NA, Francis JM, Holloway CJ, Myerson SG, Neubauer S. Feasibility and safety of high-dose adenosine perfusion cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance. 2010 Nov 16;12:66.PMID: 21080924
  • Holloway C. Betts, T. Neubauer, S, Myerson, S. Hypertrophic Cardiomyopathy with aneurysm, and thrombus, presenting as ventricular tachycardia. Journal of the American College of Cardiology. 2010 Nov 30;56(23):1961
  • Codreanu I, Robson M, Golding S,Jung B,Clarke K, Holloway CJ Longitudinally and circumferentially directed movements of the left ventricle studied by cardiovascular magnetic resonance phase contrast velocity mapping. Journal of Cardiovascular Magnetic Resonance. 2010 Aug 17;12:48.
  • Trivedi P, Canavan J, Holloway C, Slater A, Travis SPL An unusual case of dyspnoea. British Medical Journal Case Reports 2010
  • Szmigielski C, Rajpoot K, Grau V, Myerson SG, Holloway CJ, Noble JA, Kerber R, Becher H. Real-time 3D fusion echocardiography. JACC Cardiovascular Imaging. 2010 Jul;3(7):682-90.
  • Levett DZ, Martin DS, Wilson MH, Mitchell K, Dhillon S, Rigat F, Montgomery HE, Mythen MG, Grocott MP; (Holloway CJ as part of the Caudwell Xtreme Everest Research Group). Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxia. BMC Med Res Methodol. 2010 Oct 21;10:98
  • Grocott MP, Martin DS, Wilson MH, Mitchell K, Dhillon S, Mythen MG, Montgomery HE, Levett DZ; (Holloway CJ as part of the Caudwell Xtreme Everest Research Group) Caudwell xtreme Everest expedition. High Alt Med Biol. 2010 Summer;11(2):133-7.
  • Martin DS, Goedhart P, Vercueil A, Ince C, Levett DZ, Grocott MP; (Holloway CJ as part of the Caudwell Xtreme Everest Research Group) Changes in sublingual microcirculatory flow index and vessel density on ascent to altitude.Group. Exp Physiol. 2010 Aug;95(8):880-91. Epub 2010 Apr 23
  • Grocott MP, Martin DS, Levett DZ, McMorrow R, Windsor J, Montgomery HE; (Holloway CJ as part of the Caudwell Xtreme Everest Research Group). Arterial blood gases and oxygen content in climbers on Mount Everest. New England Journal of Medicine. 2009 Jan 8;360(2):140-9
  • Karamitsos, T, Holloway C, Neubauer, S. Case Report: Myocardial scarring from 2 distinct pathologies, Journal of Cardiovascular Magnetic Resonance, Number 08-21: 2008
  • Tyler D, Emmanuel Y, Cochlin L, Hudsmith L, Holloway CJ, Neubauer S. Reproducibility of 31P Magnetic Resonance Spectroscopy at 3 Telsa. NMR in Biomedicine, 2008; May 22(4)405-413
  • Grocott, M (Holloway CJ as part of the Caudwell Xtreme Everest Research Group) Genetophysiology: Using genetic strategies to explore hypoxic adaptation 2008 High Altitude Medicine and Biology 9 (2), pp. 123-129
  • Thompson J, Raitt J, Hutchings L, Drenos F, Bjargo E, Loset A, Grocott M, Montgomery H; (Holloway CJ as part of the Caudwell Xtreme Everest Research Group) . Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude. High Alt Med Biol. 2007 Winter;8(4):278-85.